@charset "utf-8";
/* =========================
  サブページ ステージ
========================= */
#zone_substage {
  background-image: url("/clinical-research/image/img-substage.jpg") !important;
}
.pink {
  color: #cc7983;
  margin-right: 0.3em;
}
.yel {
  color: #e9d172;
  margin-right: 0.3em;
}
.flex-box {
  display: flex;
  flex-flow: wrap row;
  justify-content: space-around;
}
/* study */
.study__topro {
  background-image: url("../image/sitetop/to-professional-s.jpg");
  background-size: 100%;
  border-radius: 36px 36px 0 0;
  padding: 23px 22px 65px;
  display: flex;
  gap: 40px;
  flex-direction: column;
}
@media screen and (min-width: 769px) {
  .study__topro {
    flex-direction: row;
    border-radius: calc(95/1920*100vw) calc(95/1920*100vw) 0 0;
  }
}
.study__topro-inner {
  padding: 20px 15px 15px;
  border: solid 1px #fff;
  border-radius: 25px;
  display: flex;
  flex-direction: column;
  align-items: center;
  gap: 15px;
}
.study__topro-inner h2 {
  font-size: 23px;
  text-align: center;
  font-weight: 400;
  order: -2;
}
/* ---------- menu ---------- */
.study__topro-menu {
  position: relative;
  z-index: 2;
}
.study__topro-menu li {
  margin: 10px 0;
}
.study__topro-menu li a {
  display: flex;
  align-items: center;
}
.study__topro-menu img {
  width: 7px;
  margin-right: 0.5em;
}
/* ---------- image ---------- */
.study__topro-image {
  width: clamp(130px, 26vw, 200px);
  height: clamp(130px, 26vw, 200px);
  position: relative;
  pointer-events: none; /* ← これがないと hover できない */
  order: -1;
}
.study__topro-image li {
  position: absolute;
  inset: 0;
  opacity: 0;
  border: solid 3px #fff;
  border-radius: 50%;
  transition: opacity 0.4s ease;
}
.study__topro-image li.active {
  opacity: 1;
}
.study__topro-image img {
  width: 100%;
  height: 100%;
  object-fit: cover;
}
.study__topro-image li:first-child {
  opacity: 1;
}
@media screen and (min-width: 769px) {
  .study__topro {
    padding: 5% 7% 10%;
  }
  .study__topro-inner {
    width: 100%;
    max-width: 1601px;
    margin: 0 auto;
    padding: 5% 9%;
    align-items: flex-start;
    position: relative;
  }
  .study__topro-inner h2 {
    font-size: 47px;
  }
  .study__topro-menu {
    display: flex;
    flex-direction: column;
  }
  .study__topro-menu li {
    margin: 20px 0;
  }
  .study__topro-menu li a {
    font-size: 20px;
  }
  .study__topro-menu img {
    width: 11px;
    margin-right: 1em;
  }
  .study__topro-image {
    width: clamp(300px, calc(358/1920*100vw), 358px);
    height: clamp(300px, calc(358/1920*100vw), 358px);
    position: absolute !important;
    right: 7%;
    top: 0;
    bottom: 0;
    margin: auto;
  }
  .study__topro-image li {
    border: solid 10px #fff;
  }
}
@media screen and (min-width: 1279px) {
  .study__topro-menu {
    width: 74%;
    flex-flow: wrap;
    flex-direction: row;
  }
  .study__topro-menu li {
    width: 50%;
  }
}
.study__details a {
  text-decoration: underline;
}
.study__lch {
  margin-top: -40px;
  border-radius: 36px 36px 0 0;
  padding: 40px 30px;
  background-image: linear-gradient(130deg, rgba(236, 245, 211, 1), rgba(206, 226, 200, 1));
}
.study__lch h2 {
  font-size: 18px;
  text-align: center;
  margin-bottom: 1em;
}
@media screen and (min-width: 769px) {
  .study__lch {
    margin-top: -5%;
    border-radius: calc(95/1920*100vw) calc(95/1920*100vw) 0 0;
    padding: 5% 7%;
  }
  .study__lch h2 {
    font-size: 36px;
    margin-bottom: 1.5em;
  }
  .study__lch .study__lch-txt {
    display: flex;
    align-items: stretch;
  }
  .study__lch .study__lch-txt > div {
    width: 50%;
    padding: 20px 5%;
  }
  .study__lch .study__lch-txt > div:nth-of-type(1) {
    border-right: solid 1px #009f6c;
  }
}
.study__details h3 {
  font-size: 11px;
  border: solid 1px #007e6c;
  margin: 20px auto;
  text-align: center;
  width: 92%;
  padding: 6px;
  border-radius: 26px;
}
.study__details .flex-box {
  width: 95%;
  margin: 30px auto;
}
.study__details-box {
  border: solid 1px #333;
}
.study__details-box > h4 {
  width: 80%;
  font-size: 16px;
  font-weight: 400;
  text-align: center;
  padding: 15px;
  background-image: url("../../image/sitetop/study-ttl-back.png");
  background-size: 297px 100%;
  background-repeat: no-repeat;
  background-position: center;
  margin: 0 auto;
}
.study__details-box > h4 span:not(.yel) {
  font-size: 12px;
  display: block;
}
.study__details .flex-box > div {
  width: 45%;
}
.border-box {
  margin: 15px 0;
  border: solid 1px #333;
  padding: 15px 20px;
}
.border-box h5 {
  font-size: 13px;
  margin: 0 0 15px;
}
.study__details-box dt, .study__details-box dd {
  font-size: 11px;
}
.study__details .flex-box dt {
  display: flex;
  align-items: center;
  justify-content: space-between;
  position: relative;
}
.study__details .flex-box dt .icon.arrow {
  transition: all 0.45s cubic-bezier(0.65, 0, 0.076, 1);
  left: 0.625rem;
  width: 1.125rem;
  height: 0.1rem;
  background: none;
}
.study__details .flex-box dt .icon.arrow::before {
  position: absolute;
  content: "";
  top: 21px;
  right: 0.0625rem;
  width: 0.625rem;
  height: 0.625rem;
  border-top: 0.125rem solid #91C0CC;
  border-right: 0.125rem solid #91C0CC;
  transform: rotate(45deg);
}
.study__details-box .wrap {
  padding: 40px 0;
}
.study__details .flex-box:nth-of-type(2) h4 {
  font-size: 14px;
  text-align: center;
}
.study__details .flex-box img {
  width: 74px;
  display: block;
  margin: 15px auto;
}
.green-back, .yellow-back, .purple-back {
  position: relative;
  background-color: #fff;
}
.green-back::before, .yellow-back::before, .purple-back::before {
  content: '';
  width: 100%;
  height: 100%;
  display: block;
  position: absolute;
  top: 10px;
  left: 10px;
  z-index: -1;
}
.green-back::before {
  background-color: #bcd09740;
}
.yellow-back::before {
  background-color: #ffd09740;
}
.purple-back::before {
  background-color: #c9bed740;
}
@media screen and (max-width: 768px) {
  .border-box {
    font-size: 11px;
  }
}
@media screen and (min-width: 769px) {
  .study__details {
    width: calc(1820/1920*100%);
    max-width: 1820px;
    margin: 50px auto;
  }
  .study__details h3 {
    font-size: 18px;
    width: 670px;
  }
  .study__details-box {
    padding: 2% 4%;
  }
  .border-box {
    padding: 10px;
  }
  .study__details-box > h4 {
    background-size: 634px 100%;
    font-size: 21px;
    margin-bottom: 2%;
  }
  .study__details-box > h4 span:not(.yel) {
    font-size: 18px;
  }
  .border-box h5 {
    font-size: 18px;
    text-align: center;
  }
  .study__details .flex-box {
    margin: 40px auto;
  }
  .study__details .flex-box > div {
    width: 47%;
  }
  .study__details .flex-box dl {
    display: flex;
    align-items: center;
  }
  .study__details .flex-box dt {
    width: 50%;
    font-size: 18px;
    padding: 10px 10px 10px 10px;
  }
  .study__details .flex-box dt::after {
    width: 8px;
    height: 17px;
  }
  .study__details .flex-box dd {
    width: 50%;
    font-size: 13px;
    padding: 10px 0 10px 20px;
    line-height: 1.3;
  }
  .study__details .flex-box:nth-of-type(2) h4 {
    font-size: 21px;
    display: flex;
    justify-content: center;
    align-items: center;
  }
  .study__details .flex-box img {
    width: 72px;
    margin: 20px;
  }
  .study__details .flex-box:nth-of-type(2) > div:nth-of-type(2) h4 {
    flex-direction: row-reverse;
  }
  .green-back::before, .yellow-back::before, .purple-back::before {
    top: 20px;
    left: 20px;
  }
}
@media screen and (max-width: 1278px) {
  .study__details .flex-box dl {
    flex-direction: column;
  }
  .study__details .flex-box dt {
    width: 100%;
  }
  .study__details .flex-box dd {
    width: 100%;
  }
}